Found 35 matching trials
A Study to Investigate the Interaction Between ACT-246475 and Clopidogrel, Prasugrel, and Ticagrelor in Healthy Subjects PHASE1 The primary objective of this study is to assess the pharmacodynamic (PD) e...
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STrategic Reperfusion in Elderly Patients Early After Myocardial Infarction PHASE4 In patients ≥ 60yrs with acute ST-elevation myocardial infarction randomise...
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Liverpool Hospital - Cardiology Department
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Short-term Dual Antiplatelet Therapy After Deployment of Bioabsorbable Polymer Everolimus-eluting Stent NA To compare the clinical outcomes of P2Y12 antagonist monotherapy with aspir...
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Gangnam Severance Hospital
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Cangrelor Following Ticagrelor Loading vs Ticagrelor Loading Alone in STEMI PHASE4 Platelets and thrombus formation play a key role in the pathogenesis of acu...
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Attikon University Hospital
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Post-operative Treatment of Diabetic Peripheral Arterial Disease Guided by Platelet Reactivity Unit NA To compare the effect of PRU(platelet (P2Y12) reaction units)-guided treatm...
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Multiple Locations
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Pharmacogenomics in Prediction of Cardiovascular Drugs Adverse Reaction N/A The research is planned as a prospective nested case-control study. The pla...
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Efficacy and Safety of Individualized P2Y12 Receptor Antagonists Treatment Based on Agregometry Versus Fixed Dose Regimen in Patients After Acute Myocardial Infarction PHASE4 The specific goal of this study is to determine whether the individualized ...
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Uhiversity hospital Center Zagreb
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Prasugrel Or Ticagrelor De-escalation in NSTE-ACS PHASE3 The PROTEUS study is a randomized, cross-over, open-label, pharmacodynamic ...
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Department of Cardiology, Dr. A. Jurasz University Hospital, Collegium Medicum, Nicolaus Copernicus University
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Escalated Single Platelet Inhibition for One Month Plus NOAC in Patients With Atrial Fibrillation and ACS Undergoing PCI PHASE4 The selection of the optimal antithrombotic therapy in patients with nonval...
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Medizinische Universität Innsbruck Universitätsklinik für Innere Medizin III - Kardiologie und Angiologie Anichstraße 35 6020 Innsbruck, Austria
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A Medical Research Study to Evaluate the Effects of ACT-246475 in Adults With Coronary Artery Disease PHASE2 The goal of this study is to find out if a drug called selatogrel (ACT-2464...
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University of Florida (UF) Jacksonville
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